Key words: Dermatitis; Still’s disease; Steroids Introduction Adult onset Still’s disease (AOSD) is an inflammatory disorder, which is a ver y uncommon disease, with occurrence rate of cases per , people . It is characterized by fever, arthralgia, rash, and occasionally lymphadenopathy and splenomegaly. Chronic granulomatous disease (CGD) is a rare primary immunodeficiency characterized by recurrent life-threatening bacterial and fungal infections, granuloma formation and intestinal disease. CGD is a recessive genetic disorder caused by a defect in one of five genetic loci coding for NADPH oxidase, a critical enzyme required in the phagocytosis . Granulomas Formation in Lymph Nodes, Liver and Spleen in Adult-Onset Still’s Disease: Adult-onset Still’s disease; Granulomatous; Lymphad-.